Subcutaneous Administration of Bortezomib: Strategies to Reduce Injection Site Reactions

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Subcutaneous Administration of Bortezomib: Strategies to Reduce Injection Site Reactions

Bortezomib (Velcade) is approved by the FDA for IV or SC injection in select patients with multiple myeloma or mantle cell lymphoma. The SC route functions as an alternative to IV administration for patients with poor IV access. Learn about effective strategies used to reduce injection site reactions that can occur with SC delivery.

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Subcutaneous injection is now commonly used as a standard for bortezomib administration. The bortezomib (Velcade(®)) product monograph recommends that intravenous injections be prepared at a concentration of 1 mg/mL, while subcutaneous injections may be prepared at a concentration of 2.5 mg/mL. Many institutions and subcutaneous administration guidelines use 2 mL as the maximum volume for subcu...

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ژورنال

عنوان ژورنال: Journal of the Advanced Practitioner in Oncology

سال: 2012

ISSN: 2150-0878

DOI: 10.6004/jadpro.2012.3.6.8